产品货号:
Z13015
中文名称:
CIDEB抗体
英文名称:
Anti-CIDEB Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CIDEB Antibody |
指标别名 | Cell death activator CIDE B;CIDEB |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CIDEB |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CIDE-B antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B.The immunogen is located within the last 50 amino acids of CIDE-B. |
计算分子量 | 25kDa |
成分 | CIDE-B Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CIDE-B Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N,which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-B induces apoptosis,which is inhibited by DFF45.CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation.CIDE-B is expressed mainly in liver and at lower levels in spleen,kidney,peripheral blood lymphocytes and bone marrow. |
Uniprot ID | Q9UHD4 |
基因名全称 | Cell death-inducing DFFA-like effector b |
蛋白名全称 | Cell death-inducing DFFA-like effector b |
推荐稀释比 | CIDE-B antibody can be used for detection of CIDE-B by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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